Effects on Neurons and Hippocampal Slices by Single and Multiple Primary Blast Pressure Waves From Detonating Spherical Cyclotrimethylenetrinitramine (RDX) Explosive Charges
نویسندگان
چکیده
منابع مشابه
In vitro studies of primary explosive blast loading on neurons.
In a military setting, traumatic brain injury (TBI) is frequently caused by blast waves that can trigger a series of neuronal biochemical changes. Although many animal models have been used to study the effects of primary blast waves, elucidating the mechanisms of damage in a whole-animal model is extremely complex. In vitro models of primary blast, which allow for the deconvolution of mechanis...
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Noise produced by blast waves can be a problem, especially when an explosion occurs near populated areas. As one means of reducing the blast noise, the explosive is detonated in a pit, a space closed at the bottom and sides, open at the top. A two-dimentional finite difference model was used to simulate such an explosion in a pit and to determine to what extent the blast wave was attenuated. Th...
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Endogenous waves in hippocampal slices.
Sharp waves (SPWs) are thought to play a major role in intrinsic hippocampal operations during states in which subcortical and cortical inputs to hippocampus are reduced. This study describes evidence that such activity occurs spontaneously in appropriately prepared rat hippocampal slices. Irregular waves, with an average frequency of approximately 4 Hz, were recorded from field CA3 in slices p...
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ژورنال
عنوان ژورنال: Military Medicine
سال: 2018
ISSN: 0026-4075,1930-613X
DOI: 10.1093/milmed/usx158